I haven't had any problems so far. But I've mostly only done W-2s and 1099s. I also Print/Pdf from the custom button, not the Preparer Copy button.
Also, I separate my PDF files into the Fed return, State return, other categories, including the statements/worksheets. I remember when PDFing my other statements/worksheets and including the various Assets/Depreciation schedules, the PDF function would hang up. I started to PDF my Assets/Depreciation schedules separately. This made smaller files to PDF and everything worked fine.